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user_select="" content_alignment_medium="" content_alignment_small="" content_alignment="" disable_idd="no" hide_on_mobile="small-visibility,medium-visibility,large-visibility" sticky_display="normal,sticky" class="" id="" html_attributes="W10=" width_medium="" width_small="" width="" min_width_medium="" min_width_small="" min_width="" max_width_medium="" max_width_small="" max_width="" margin_top_medium="" margin_right_medium="" margin_bottom_medium="" margin_left_medium="" margin_top_small="" margin_right_small="" margin_bottom_small="" margin_left_small="" margin_top="" margin_right="" margin_bottom="" margin_left="" fusion_font_family_text_font="" fusion_font_variant_text_font="" font_size="" line_height="" letter_spacing="" text_transform="" text_color="" render_logics="" logics="" animation_type="" animation_direction="left" animation_color="" animation_speed="0.3" animation_delay="0" animation_offset=""] Pri približno polovici bolnikov s kožnim melanomom je prisotna mutacija gena BRAF . Pri teh bolnikih je mogoče uporabiti tarčna zdravila, ki zavirajo delovanje spremenjenih beljakovin in s tem upočasnijo ali ustavijo rast tumorskih celic. Najpogosteje se uporabljajo kombinacije zaviralcev BRAF in MEK, saj so učinkovitejše kot zdravljenje z enim samim zdravilom. Tarčno zdravljenje se uporablja predvsem: po operaciji pri bolnikih z mutacijo BRAF in večjim tveganjem za ponovitev bolezni, pri napredovalem ali metastatskem melanomu. Pred uvedbo tarčnega zdravljenja je vedno potrebna molekularna analiza tumorja. [/fusion_text][/fusion_builder_column][/fusion_builder_row][/fusion_builder_container]

Tarčno zdravljenje

Pri približno polovici bolnikov s kožnim melanomom je prisotna mutacija gena BRAF.

Pri teh bolnikih je mogoče uporabiti tarčna zdravila, ki zavirajo delovanje spremenjenih beljakovin in s tem upočasnijo ali ustavijo rast tumorskih celic.

Najpogosteje se uporabljajo kombinacije zaviralcev BRAF in MEK, saj so učinkovitejše kot zdravljenje z enim samim zdravilom.

Tarčno zdravljenje se uporablja predvsem:

po operaciji pri bolnikih z mutacijo BRAF in večjim tveganjem za ponovitev bolezni,
pri napredovalem ali metastatskem melanomu.

Pred uvedbo tarčnega zdravljenja je vedno potrebna molekularna analiza tumorja.

LK2026-09-20T09:17:50+02:00

Zaloška cesta 2

1000 Ljubljana, Slovenija
T: 064 12 44 66
E: info@melanoma.si

Nacionalno društvo bolnikov z melanomom je prostovoljna in neprofitna organizacija, ki deluje na področju preventive, zgodnjega odkrivanja melanoma, podpore bolnikom ter ozaveščanja javnosti.
S povezovanjem bolnikov, zdravstvenih strokovnjakov, raziskovalcev in drugih partnerjev si prizadevamo zmanjšati breme melanoma v Sloveniji ter izboljšati kakovost življenja bolnikov in njihovih svojcev.

Tarčno zdravljenje

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